SCHEMBL8771126

SCHEMBL8771126

C=CCOC(=O)C(O)CCCCCC

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
GPR84 Q9NQS5 7/20 0.52
FFAR1 O14842 2/20 0.52
ZDHHC7 Q9NXF8 1/20 0.42
ABCB1 P08183 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
NAAA Q02083 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL671482 1.00 TSHR (0.57) TSHRGPR84FFAR1ZDHHC7ABCB1
SCHEMBL154641 0.98 TSHR (0.54) TSHRGPR84FFAR1ZDHHC7ABCB1
SCHEMBL1871016 0.98 TSHR (0.54) TSHRGPR84FFAR1ZDHHC7ABCB1
SCHEMBL1685294 0.93 TSHR (0.51) TSHRGPR84FFAR1TDP1
SCHEMBL6131095 0.91 TSHR (0.47) TSHRGPR84FFAR1ZDHHC7ABCB1
Decylacetate SCHEMBL21837279 0.90 TSHR (0.48) TSHRGPR84FFAR1NAAAMAPT
SCHEMBL5403623 0.88 TSHR (0.49) TSHRGPR84FFAR1ZDHHC7ABCB1
SCHEMBL1081673 0.86 TSHR (0.50) TSHRGPR84FFAR1ZDHHC7ABCB1
SCHEMBL9323925 0.85 TSHR (0.46) TSHRGPR84FFAR1TDP1MAPT
SCHEMBL22598182 0.84 TSHR (0.59) TSHRGPR84FFAR1ZDHHC7TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0451668-B1 Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates CHISSO CORP (JP) 1997-08-13 EP claimed
CN-109803632-A High performance, high impact strength fragrance emitting accord 国际香料和香精公司 2019-05-24 CN disclosed
CN-105228993-B Compound and its purposes as spices 西姆莱斯股份公司 2018-02-13 CN disclosed
EP-0451668-A2 Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof CHISSO CORPORATION (JP) 1991-10-16 EP disclosed