Phenol

Phenol

SCHEMBL6131166

C=O.CCNc1ccccc1.CNc1ccccc1.Oc1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
LMNA P02545 1/20 0.46
HIF1A Q16665 3/20 0.43
ALDH1A1 P00352 3/20 0.43
THRB P10828 2/20 0.43
RECQL P46063 2/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
CASP1 P29466 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ADRA2A P08913 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
NPC1 O15118 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
RAB9A P51151 1/20 0.39
APP P05067 3/20 0.39
TDP1 Q9NUW8 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL6131170 0.94 LMNA (0.49) TSHRLMNAHIF1AALDH1A1THRB
Phenol SCHEMBL6131165 0.93 LMNA (0.52) TSHRLMNAHIF1AALDH1A1THRB
Phenol SCHEMBL6131175 0.87 TSHR (0.64) TSHRLMNAHIF1AALDH1A1THRB
Phenol SCHEMBL7546804 0.87 LMNA (0.52) TSHRLMNAHIF1AALDH1A1THRB
SCHEMBL11616572 0.85 TSHR (0.67) TSHRLMNAALDH1A1CYP3A4HSD17B10
Phenol SCHEMBL9774383 0.83 CYP3A4 (0.52) TSHRLMNAHIF1AALDH1A1TP53
Phenol SCHEMBL28085320 0.81 TSHR (0.74) TSHRLMNAHIF1AALDH1A1THRB
Bicarbonate SCHEMBL28218650 0.77 LMNA (0.55) TSHRLMNAALDH1A1TP53CYP3A4
Methyl Alcohol SCHEMBL5316416 0.77 LMNA (0.57) TSHRLMNAALDH1A1HSD17B10ADRA2A
SCHEMBL20542806 0.77 LMNA (0.57) TSHRLMNAALDH1A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050003202-A1 N-substituted arylamino-phenol-formaldehyde condensates BORDEN CHEMICAL FOUNDRY, LLC 2005-01-06 US disclosed
US-6780511-B2 METHANOL TOLERANCE, SOLVENT SOLUBILITY; SELF-CATALYZING CURING AGENTS FOR EPOXY RESINS BORDEN CHEMICAL, INC. 2004-08-24 US disclosed
US-20040048072-A1 N-substituted arylamino-phenol-formaldehyde condensates BORDEN CHEMICAL, INC. 2004-03-11 US disclosed