SCHEMBL6131250

SCHEMBL6131250

C=C(C=C(CCCOCCCC)C(=O)O)C(=O)OCCCC

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
HPGD P15428 1/20 0.40
ATM Q13315 1/20 0.39
HCAR2 Q8TDS4 3/20 0.38
ALDH1A1 P00352 1/20 0.37
APEX1 P27695 3/20 0.33
THRB P10828 1/20 0.33
PTGES O14684 2/20 0.32
ALOX5 P09917 2/20 0.32
PPARG P37231 1/20 0.32
PLA2G4B P0C869 1/20 0.32
RARB P10826 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6710667 0.90 TSHR (0.41) TSHRHPGDATMHCAR2ALDH1A1
SCHEMBL7943868 0.88 TSHR (0.53) TSHRHPGDHCAR2APEX1
SCHEMBL10950921 0.85 TSHR (0.39) TSHRHPGDATMHCAR2ALDH1A1
SCHEMBL8006266 0.85 TSHR (0.49) TSHRHCAR2THRB
SCHEMBL14778275 0.81 HCAR2 (0.37) TSHRHPGDHCAR2THRB
SCHEMBL3406538 0.79 TSHR (0.59) TSHRHPGDATMHCAR2ALDH1A1
SCHEMBL10904258 0.79 TSHR (0.39) TSHRHPGDATMHCAR2ALDH1A1
SCHEMBL168598 0.78 TSHR (0.50) TSHRHPGDATMHCAR2ALDH1A1
Methacrylic Acid SCHEMBL725335 0.76 TSHR (0.51) TSHRHPGDATMHCAR2ALDH1A1
SCHEMBL8997946 0.76 APEX1 (0.40) TSHRALDH1A1APEX1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050032008-A1 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. 2005-02-10 US disclosed
US-6844146-B2 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-01-18 US disclosed