Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006266 | 0.93 | TSHR (0.49) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL6131250 | 0.88 | TSHR (0.41) | TSHRHCAR2HPGDAPEX1 | |
| SCHEMBL6710667 | 0.87 | TSHR (0.41) | TSHRHCAR2HPGDAPEX1 | |
| SCHEMBL10953969 | 0.82 | TSHR (0.65) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL27816436 | 0.82 | TSHR (0.65) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL6274865 | 0.82 | TSHR (0.60) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL28078386 | 0.82 | TSHR (0.60) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL14660709 | 0.82 | TSHR (0.60) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL17063567 | 0.82 | TSHR (0.60) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL10950921 | 0.82 | TSHR (0.39) | TSHRHCAR2NPSR1EPHX1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6270615-B1 | THERMOPLASTIC RESIN | KANEKA CORPORATION (JP) | 2001-08-07 | — | — | US | claimed |
| US-6270615-B1 | THERMOPLASTIC RESIN | KANEKA CORPORATION (JP) | 2001-08-07 | — | — | US | disclosed |