Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 3/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206187 | 0.90 | CXCR4 (0.51) | CXCR4ADAMTS4ADAMTS5LMNASMN1; SMN2 | |
| SCHEMBL1205649 | 0.88 | CXCR4 (0.53) | CXCR4ADAMTS4ADAMTS5LMNASMN1; SMN2 | |
| SCHEMBL1205454 | 0.85 | CXCR4 (0.52) | CXCR4ADAMTS4ADAMTS5LMNAKCNA5 | |
| SCHEMBL1206147 | 0.85 | CXCR4 (0.55) | CXCR4ADAMTS4ADAMTS5LMNASMN1; SMN2 | |
| SCHEMBL1206642 | 0.83 | CXCR4 (0.70) | CXCR4ADAMTS4ADAMTS5LMNASMN1; SMN2 | |
| SCHEMBL1206108 | 0.82 | CXCR4 (0.56) | CXCR4ADAMTS4ADAMTS5LMNAKCNA5 | |
| SCHEMBL1205659 | 0.81 | CXCR4 (0.48) | CXCR4ADAMTS4ADAMTS5SMN1; SMN2KCNA5 | |
| SCHEMBL3737249 | 0.80 | CXCR4 (0.49) | CXCR4KCNA5KMT2ATSHRMEN1 | |
| SCHEMBL1205651 | 0.79 | OPRK1 (0.39) | CXCR4LMNASMN1; SMN2KMT2ATSHR | |
| SCHEMBL1205272 | 0.76 | CXCR4 (0.69) | CXCR4LMNASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1550657-A1 | AMINE COMPOUNDS AND USE THEREOF | Kureha Chemical Industry Co., Ltd. (JP) | 2005-07-06 | — | — | EP | disclosed |