SCHEMBL6131634

SCHEMBL6131634

O=[N+]([O-])c1nccn1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1979557 0.74
SCHEMBL3955047 0.74
SCHEMBL196953 0.74 CA12 (0.41)
SCHEMBL17635577 0.74
SCHEMBL4262422 0.74
SCHEMBL6236180 0.74
SCHEMBL22426748 0.74 CA12 (0.39)
SCHEMBL11390072 0.72 CA12 (0.64)
SCHEMBL22462573 0.72 CA12 (0.44)
SCHEMBL2552403 0.71 CA12 (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117222890-A Analytical HPLC 通用电气健康护理有限公司 2023-12-12 CN claimed
CN-115731316-A Image reconstruction method and system 上海联影医疗科技股份有限公司 2023-03-03 CN disclosed
CN-111574515-B Preparation method and purification method of organic fluorinated aliphatic compound 财团法人峨山社会福祉财团 2023-01-10 CN disclosed
US-6958141-B2 Rhenium and technetium complexes containing a hypoxia-localizing moiety BRACCO INTERNATIONAL B.V. (NL) 2005-10-25 US disclosed
US-20020054853-A1 Rhenium and technetium complexes containing a hypoxia-localizing moiety BRACCO SUISSE SA (CH) 2002-05-09 US disclosed
CN-1055685-C Heteroatom-bearing ligands and metal complexes thereof BRAKER INTERNAT B V (NL) 2000-08-23 CN disclosed
US-5808091-A DIAGNOSTIC IMAGING AGENT BRACCO INTERNATIONAL B.V. 1998-09-15 US disclosed
US-5741912-A DIAGNOSIS, THERAPY BRACCO INTERNATIONAL B.V. 1998-04-21 US disclosed
US-5688487-A Diagnostic imaging methods using rhenium and technetium complexes containing a hypoxia-localizing moiety BRACCO INTERNATIONAL B.V. (NL) 1997-11-18 US disclosed
CN-1093084-A The rhenium and the technetium complex that comprise the anoxic localization part SQUIBB & SONS INC (US) 1994-10-05 CN disclosed
CN-1071928-A The rhenium and the technetium complex that comprise the anoxic localization part SQUIBB & SONS INC (US) 1993-05-12 CN disclosed