Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2988304 | 1.00 | ITGB1 (0.50) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL2976280 | 0.93 | ITGB1 (0.48) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL5179350 | 0.93 | ITGB1 (0.48) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL2978337 | 0.93 | ITGB1 (0.58) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL3884133 | 0.93 | ITGB1 (0.58) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL3836314 | 0.92 | ITGB1 (0.44) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL6131688 | 0.92 | ITGB1 (0.44) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL3835544 | 0.92 | ITGB1 (0.51) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL2978080 | 0.88 | ITGB1 (0.45) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL3836794 | 0.86 | ITGA4 (0.43) | ITGB1ITGA4CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878718-B2 | Phenylalanine enamide derivatives | CELLTECH R&D LIMITED (GB) | 2005-04-12 | — | — | US | disclosed |
| US-20050038084-A1 | Phenylalanine enamide derivatives | CELLTECH R&D LIMITED | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038084-A1 | Phenylalanine enamide derivatives | PAH, ARRB1, ACVR2B | ITGB1 34/4885ITGA4 316/4885CYP3A4 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.