Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK2 | Q16620 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RHOC | P08134 | 2/20 | 0.40 |
| ▸ | RHOA | P61586 | 2/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | NNMT | P40261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519584 | 0.83 | NPC1 (0.53) | HTTHPGDPOLBGSTO1NPC1 | |
| SCHEMBL3321012 | 0.82 | NTRK2 (0.65) | NTRK2HTTHPGDPOLBALDH1A1 | |
| SCHEMBL6936998 | 0.79 | KMT2A (0.48) | HTTHPGDPOLBGSTO1MITF | |
| SCHEMBL4582151 | 0.78 | NPC1 (0.39) | HTTPOLBGSTO1NPC1MITF | |
| SCHEMBL782086 | 0.77 | GAA (0.56) | HTTPOLBNPC1MITFRAB9A | |
| SCHEMBL9717473 | 0.76 | NTRK2 (0.59) | NTRK2HTTHPGDPOLBALDH1A1 | |
| SCHEMBL31669637 | 0.76 | SMN1; SMN2 (0.48) | NTRK2HTTHPGDPOLBALDH1A1 | |
| SCHEMBL4581493 | 0.76 | ALDH1A1 (0.47) | NTRK2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL4583058 | 0.75 | ALDH1A1 (0.43) | NTRK2POLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4583067 | 0.75 | ALDH1A1 (0.46) | NTRK2POLBNPC1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875864-B2 | Aminocarboxylate ligands having substituted aromatic amide moieties | BRACCO INTERNATIONAL B.V. (NL) | 2005-04-05 | — | — | US | disclosed |