Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7686966 | 0.99 | KDM4E (0.53) | KDM4EALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL6131973 | 0.85 | HRH3 (0.56) | KDM4EALDH1A1MAPTKMT2AGAA | |
| Water SCHEMBL7691512 | 0.84 | HRH3 (0.55) | KDM4EALDH1A1MAPTKMT2AGAA | |
| Water SCHEMBL6131839 | 0.84 | HRH3 (0.55) | KDM4EALDH1A1MAPTKMT2AGAA | |
| SCHEMBL6131851 | 0.79 | OGA (0.59) | KDM4EALDH1A1KMT2AACHEHPGD | |
| SCHEMBL6131984 | 0.79 | UTS2R (0.49) | KDM4EALDH1A1MAPTL3MBTL1GAA | |
| Water SCHEMBL7685626 | 0.78 | OGA (0.58) | KDM4EALDH1A1KMT2AACHEHPGD | |
| Water SCHEMBL6131870 | 0.78 | OGA (0.58) | KDM4EALDH1A1KMT2AACHEHPGD | |
| Hydrochloric Acid SCHEMBL6132096 | 0.77 | UTS2R (0.48) | KDM4EALDH1A1MAPTL3MBTL1GAA | |
| SCHEMBL6131939 | 0.76 | GAA (0.55) | KDM4EALDH1A1MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |