Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132092 | 1.00 | GAA (0.55) | GAATDP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10335578 | 0.90 | GAA (0.56) | GAATDP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10335328 | 0.90 | GAA (0.56) | GAATDP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5351001 | 0.85 | PDE4B (0.55) | POLB | |
| SCHEMBL5350996 | 0.85 | PDE4B (0.55) | POLB | |
| SCHEMBL5351006 | 0.85 | PDE4B (0.55) | POLB | |
| SCHEMBL27424699 | 0.85 | RECQL (0.44) | GAATDP1ALDH1A1KDM4EHTT | |
| SCHEMBL6819120 | 0.83 | AKR1C3 (0.51) | GAATDP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6819118 | 0.83 | AKR1C3 (0.51) | GAATDP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL26667031 | 0.82 | GAA (0.48) | GAATDP1NFE2L2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214310-B1 | NOVEL PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-04-27 | — | — | EP | disclosed |
| EP-1214310-A1 | NOVEL PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2002-06-19 | — | — | EP | disclosed |
| US-6348604-B1 | COMPOUNDS IN WHICH SELECTION AND PLACEMENT OF SUBSTITUENTS CONTROL WAVELENGTH AND/OR INTENSITY OF VISIBLE ABSORBANCE BANDS | PPG INDUSTRIES OHIO, INC. | 2002-02-19 | — | — | US | disclosed |
| WO-2001019812-A1 | NOVEL PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-03-22 | — | — | WO | disclosed |