Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131908 | 0.90 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNATSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL6132036 | 0.90 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNATSHRMAPK1 | |
| SCHEMBL6131872 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KDM4ELMNATSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL6131888 | 0.87 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNATSHRMAPK1 | |
| SCHEMBL6131916 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4ELMNATSHRMAPK1 | |
| SCHEMBL6131859 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNATSHRMAPK1 | |
| SCHEMBL6131848 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNATSHRMAPK1 | |
| SCHEMBL7686968 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNATSHRMAPK1 | |
| SCHEMBL6131832 | 0.84 | KDM4E (0.63) | ALDH1A1KDM4EMAPK1KMT2ABCHE | |
| Hydrochloric Acid SCHEMBL7690284 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4ELMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6479495-B1 | SIMULTANEOUSLY TREATING DEPRESSION AND MEMORY DYSFUNCTION IN MAMMALS SUFFERING FROM MEMORY DYSFUNCTION AND DEPRESSION | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |