Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2025672 | 0.81 | TSHR (0.52) | IDO1AGXTTSHRLIPEALDH1A1 | |
| SCHEMBL3080694 | 0.81 | TSHR (0.52) | IDO1AGXTTSHRLIPEALDH1A1 | |
| Boric Acid SCHEMBL28556682 | 0.79 | TSHR (0.50) | IDO1AGXTTSHRLIPEALDH1A1 | |
| SCHEMBL933492 | 0.77 | LIPE (0.50) | IDO1AGXTTSHRLIPEALDH1A1 | |
| SCHEMBL22006983 | 0.77 | IDO1 (0.50) | IDO1AGXTTSHRLIPEALDH1A1 | |
| SCHEMBL3887273 | 0.76 | TSHR (0.46) | IDO1AGXTTSHRLIPEALDH1A1 | |
| SCHEMBL18550249 | 0.76 | TSHR (0.46) | IDO1AGXTTSHRLIPEALDH1A1 | |
| SCHEMBL51017 | 0.75 | TSHR (0.57) | IDO1AGXTTSHRLIPEALDH1A1 | |
| Trimethylammonium SCHEMBL11469069 | 0.74 | LIPE (0.47) | IDO1AGXTTSHRLIPEALDH1A1 | |
| Trimethylammonium SCHEMBL11469675 | 0.74 | LIPE (0.47) | IDO1AGXTTSHRLIPEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499336-A4 | PROTEASE INHIBITORS | TUFTS COLLEGE (US) | 2005-06-01 | — | — | EP | disclosed |
| EP-1499336-A2 | PROTEASE INHIBITORS | Trustees of Tufts College (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003092605-A9 | PROTEASE INHIBITORS | TUFTS COLLEGE (US) | 2004-04-08 | — | — | WO | disclosed |
| WO-2003092605-A2 | PROTEASE INHIBITORS | TRUSTEES OF TUFTS COLLEGE (US) | 2003-11-13 | — | — | WO | disclosed |