Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.57 |
| ▸ | CXCR1 | P25024 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132917 | 1.00 | SMPD1 (0.57) | SMPD1CXCR1MAPTTP53RAB9A | |
| SCHEMBL2350269 | 0.92 | SMPD1 (0.61) | SMPD1CXCR1MAPTTP53RAB9A | |
| SCHEMBL2356088 | 0.92 | SMPD1 (0.61) | SMPD1CXCR1MAPTTP53RAB9A | |
| SCHEMBL6132946 | 0.91 | CXCR1 (0.56) | SMPD1CXCR1TP53RAB9ANPC1 | |
| SCHEMBL6132835 | 0.91 | CXCR1 (0.56) | SMPD1CXCR1TP53RAB9ANPC1 | |
| SCHEMBL5147869 | 0.91 | SMPD1 (0.63) | SMPD1CXCR1MAPTRAB9ANPC1 | |
| SCHEMBL7333704 | 0.91 | SMPD1 (0.63) | SMPD1CXCR1MAPTRAB9ANPC1 | |
| SCHEMBL2351006 | 0.91 | SMPD1 (0.65) | SMPD1CXCR1MAPTRAB9ANPC1 | |
| SCHEMBL2363108 | 0.87 | SMPD1 (0.52) | SMPD1CXCR1MAPTTP53RAB9A | |
| SCHEMBL2356688 | 0.85 | SMPD1 (0.52) | SMPD1CXCR1MAPTTP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |