Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 7/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 4/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132835 | 1.00 | CXCR1 (0.56) | CXCR1SMPD1RARBABCB1ABCC1 | |
| SCHEMBL6132917 | 0.91 | SMPD1 (0.57) | CXCR1SMPD1NPC1RAB9ATP53 | |
| SCHEMBL2354881 | 0.91 | RARB (0.67) | CXCR1SMPD1RARBABCB1ABCC1 | |
| SCHEMBL6132232 | 0.91 | SMPD1 (0.57) | CXCR1SMPD1NPC1RAB9ATP53 | |
| SCHEMBL12243285 | 0.91 | RARB (0.67) | CXCR1SMPD1RARBABCB1ABCC1 | |
| SCHEMBL2353001 | 0.91 | RARB (0.67) | CXCR1SMPD1RARBABCB1ABCC1 | |
| SCHEMBL2353533 | 0.90 | RARB (0.64) | CXCR1SMPD1RARBABCB1ABCC1 | |
| SCHEMBL7403884 | 0.90 | RARB (0.64) | CXCR1SMPD1RARBABCB1ABCC1 | |
| SCHEMBL2354038 | 0.90 | SMPD1 (0.63) | CXCR1SMPD1RARBABCB1ABCC1 | |
| Ammonia Solution, Strong SCHEMBL17822400 | 0.89 | RARB (0.63) | CXCR1SMPD1RARBABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |