Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL558749 | 0.90 | MEN1 (0.54) | SMN1; SMN2HTTNPSR1MEN1KMT2A | |
| SCHEMBL1458941 | 0.86 | SMN1; SMN2 (0.70) | SMN1; SMN2HTTNPSR1MAPTLMNA | |
| SCHEMBL1779228 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2HTTNPSR1MAPTLMNA | |
| SCHEMBL1257264 | 0.81 | MEN1 (0.70) | SMN1; SMN2HTTNPSR1MAPTLMNA | |
| SCHEMBL31084016 | 0.80 | MEN1 (0.50) | SMN1; SMN2HTTNPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6132929 | 0.79 | ENPP2 (0.50) | SMN1; SMN2NPSR1MAPTLMNAALDH1A1 | |
| SCHEMBL5573222 | 0.79 | MAPT (0.76) | SMN1; SMN2HTTNPSR1MAPTLMNA | |
| SCHEMBL31276408 | 0.79 | NPSR1 (0.51) | SMN1; SMN2HTTNPSR1MAPTLMNA | |
| SCHEMBL31342184 | 0.79 | HTT (0.54) | SMN1; SMN2HTTNPSR1MAPTLMNA | |
| SCHEMBL24310164 | 0.78 | ESR2 (0.46) | SMN1; SMN2MAPTLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |