Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 6/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135547 | 0.87 | HRH3 (0.52) | MEN1KMT2AHRH3CSNK2A2CSNK2A1 | |
| Hydrochloric Acid SCHEMBL7333163 | 0.87 | KDM4E (0.55) | KDM4ERECQLALDH1A1MEN1KMT2A | |
| SCHEMBL6135376 | 0.86 | USP2 (0.55) | MEN1KMT2AHRH3CSNK2A2CSNK2A1 | |
| SCHEMBL6135370 | 0.86 | USP2 (0.55) | MEN1KMT2AHRH3CSNK2A2CSNK2A1 | |
| SCHEMBL6134406 | 0.86 | HRH3 (0.53) | MEN1KMT2AHRH3CSNK2A2CSNK2A1 | |
| SCHEMBL6134222 | 0.86 | HRH3 (0.53) | MEN1KMT2AHRH3CSNK2A2CSNK2A1 | |
| SCHEMBL6134820 | 0.85 | HRH3 (0.47) | KDM4EMEN1KMT2AHRH3CSNK2A2 | |
| SCHEMBL6132210 | 0.82 | HDAC3 (0.43) | KDM4ERECQLALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6132609 | 0.82 | HRH3 (0.44) | KDM4EMEN1KMT2AHRH3CSNK2A2 | |
| SCHEMBL6374374 | 0.80 | HRH3 (0.54) | HRH3CSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884774-B2 | Cyclic hexapeptide derivatives | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1259535-B1 | CYCLIC HEXAPEPTIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-04-13 | — | — | EP | disclosed |
| US-20030083238-A1 | Cyclic hexapeptide derivatives | ASTELLAS PHARMA INC. (JP) | 2003-05-01 | — | — | US | disclosed |
| EP-1259535-A1 | CYCLIC HEXAPEPTIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001060846-A1 | CYCLIC HEXAPEPTIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083238-A1 | Cyclic hexapeptide derivatives | NGLY1, ALG1, CHIT1 | KDM4E 4687/4885RECQL 1260/4885ALDH1A1 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.