Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132590 | 1.00 | KDM4E (0.64) | KDM4ELMNAHTTTDP1RECQL | |
| SCHEMBL6132589 | 1.00 | KDM4E (0.64) | KDM4ELMNAHTTTDP1RECQL | |
| SCHEMBL6132461 | 1.00 | KDM4E (0.64) | KDM4ELMNAHTTTDP1RECQL | |
| SCHEMBL6132643 | 0.84 | KDM4E (0.62) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL6132616 | 0.84 | KDM4E (0.62) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL6132642 | 0.84 | KDM4E (0.62) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL6132613 | 0.84 | KDM4E (0.62) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL14399556 | 0.81 | KDM4E (0.61) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL4094582 | 0.78 | KDM4E (0.73) | KDM4ETDP1RECQLKMT2AATM | |
| SCHEMBL4094589 | 0.78 | KDM4E (0.73) | KDM4ETDP1RECQLKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |