Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132613 | 1.00 | KDM4E (0.62) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL6132643 | 1.00 | KDM4E (0.62) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL6132642 | 1.00 | KDM4E (0.62) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL6132459 | 0.84 | KDM4E (0.64) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL6132589 | 0.84 | KDM4E (0.64) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL6132461 | 0.84 | KDM4E (0.64) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL6132590 | 0.84 | KDM4E (0.64) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL6132555 | 0.81 | KDM4E (0.57) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL6132808 | 0.81 | KDM4E (0.57) | KDM4ELMNAHTTTDP1ALDH1A1 | |
| SCHEMBL6132558 | 0.81 | KDM4E (0.57) | KDM4ELMNAHTTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |