Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132474 | 1.00 | MAPT (0.55) | MAPTRAB9ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL327800 | 0.77 | MAPT (0.57) | MAPTRAB9ATSHRALDH1A1KDM4E | |
| SCHEMBL18436831 | 0.77 | MAPT (0.57) | MAPTRAB9ATSHRALDH1A1KDM4E | |
| SCHEMBL24352865 | 0.77 | MAPT (0.57) | MAPTRAB9ATSHRALDH1A1KDM4E | |
| SCHEMBL7790503 | 0.77 | MAPT (0.57) | MAPTRAB9ATSHRALDH1A1KDM4E | |
| SCHEMBL23731989 | 0.77 | MAPT (0.57) | MAPTRAB9ATSHRALDH1A1KDM4E | |
| SCHEMBL6132323 | 0.77 | USP2 (0.57) | MAPTTSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6132666 | 0.77 | USP2 (0.57) | MAPTTSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6132668 | 0.77 | USP2 (0.57) | MAPTTSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6132320 | 0.77 | USP2 (0.57) | MAPTTSHRSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |