Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.40 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132320 | 1.00 | USP2 (0.57) | USP2CHEK1KDM4EMAPTKMT2A | |
| SCHEMBL6132666 | 1.00 | USP2 (0.57) | USP2CHEK1KDM4EMAPTKMT2A | |
| SCHEMBL6132668 | 1.00 | USP2 (0.57) | USP2CHEK1KDM4EMAPTKMT2A | |
| SCHEMBL6132857 | 0.96 | USP2 (0.62) | USP2CHEK1KDM4EMAPTKMT2A | |
| SCHEMBL6132861 | 0.96 | USP2 (0.62) | USP2CHEK1KDM4EMAPTKMT2A | |
| SCHEMBL607498 | 0.91 | USP2 (0.58) | USP2KDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL6132480 | 0.85 | ALDH1A1 (0.53) | KDM4EMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL6132481 | 0.85 | ALDH1A1 (0.53) | KDM4EMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL6132936 | 0.83 | CSNK2A2 (0.48) | USP2MAPTALDH1A1 | |
| SCHEMBL6132938 | 0.83 | CSNK2A2 (0.48) | USP2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |