Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132536 | 1.00 | ALDH1A1 (0.55) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL6133087 | 0.96 | ALDH1A1 (0.58) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL6133086 | 0.96 | ALDH1A1 (0.58) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL6132378 | 0.92 | ALDH1A1 (0.62) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL6132380 | 0.92 | ALDH1A1 (0.62) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL6132480 | 0.86 | ALDH1A1 (0.53) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL6132481 | 0.86 | ALDH1A1 (0.53) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL22015905 | 0.83 | HPGD (0.65) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL20188098 | 0.83 | HPGD (0.65) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL6132320 | 0.82 | USP2 (0.57) | ALDH1A1MEN1KMT2AHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |