Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6132444 | 0.88 | MAPT (0.40) | MAPTTP53LMNACA12CA1 | |
| SCHEMBL6132169 | 0.88 | MAPT (0.43) | MAPTTP53LMNACA12CA1 | |
| Hydrochloric Acid SCHEMBL6135061 | 0.87 | MAPT (0.44) | MAPTTP53LMNACA12CA1 | |
| SCHEMBL6135097 | 0.86 | MAPT (0.45) | MAPTTP53LMNACA12CA1 | |
| SCHEMBL6132698 | 0.84 | HDAC3 (0.38) | MAPTTP53LMNACA12CA1 | |
| Hydrochloric Acid SCHEMBL6133899 | 0.84 | CHEK1 (0.42) | MAPTTP53LMNACA12CA1 | |
| Hydrochloric Acid SCHEMBL6134789 | 0.84 | CHEK1 (0.42) | MAPTTP53LMNACA12CA1 | |
| SCHEMBL6132901 | 0.81 | USP2 (0.50) | MAPTLMNACHEK1USP2 | |
| SCHEMBL6133896 | 0.80 | TP53 (0.42) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL6134575 | 0.80 | TP53 (0.43) | MAPTTP53CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |