Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6132409 | 0.90 | MAPT (0.41) | MAPTLMNATP53GAASIRT2 | |
| Trifluoroacetic Acid SCHEMBL6134395 | 0.89 | MAPT (0.42) | MAPTLMNATP53GAASIRT2 | |
| SCHEMBL6132573 | 0.88 | MAPT (0.42) | MAPTLMNATP53GAACA12 | |
| Trifluoroacetic Acid SCHEMBL6134998 | 0.87 | SIRT2 (0.40) | MAPTLMNATP53SIRT2CA12 | |
| SCHEMBL6134866 | 0.83 | MAPT (0.44) | MAPTLMNATP53GAACA12 | |
| Trifluoroacetic Acid SCHEMBL7325659 | 0.83 | SIRT2 (0.46) | MAPTLMNATP53GAASIRT2 | |
| Trifluoroacetic Acid SCHEMBL7324043 | 0.82 | MTOR (0.42) | MAPTLMNATP53SIRT2CA12 | |
| Trifluoroacetic Acid SCHEMBL7323148 | 0.82 | LMNA (0.48) | MAPTLMNATP53SIRT2CA12 | |
| Trifluoroacetic Acid SCHEMBL6132999 | 0.82 | SIRT2 (0.40) | MAPTLMNATP53GAASIRT2 | |
| Trifluoroacetic Acid SCHEMBL6135113 | 0.82 | MAPT (0.40) | MAPTLMNATP53DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |