Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209493 | 0.85 | HRH3 (0.60) | HRH3KDM4ETP53MEN1 | |
| Hydrochloric Acid SCHEMBL5208875 | 0.85 | KDM4E (0.47) | HRH3KDM4ETP53CHRNA10CHRNA9 | |
| Hydrochloric Acid SCHEMBL5214091 | 0.84 | HRH3 (0.59) | HRH3KDM4ETP53MEN1 | |
| SCHEMBL5212927 | 0.82 | HRH3 (0.64) | HRH3KDM4ETP53CHRNA10CHRNA9 | |
| Hydrochloric Acid SCHEMBL5211632 | 0.81 | HRH3 (0.63) | HRH3KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL6132921 | 0.81 | ADRB1 (0.49) | KDM4E | |
| SCHEMBL20346944 | 0.81 | KDM4E (0.53) | HRH3KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL3094565 | 0.78 | KDM1A (0.43) | HRH3GPR119 | |
| SCHEMBL139427 | 0.77 | KDM4E (0.66) | HRH3KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL149656 | 0.77 | KDM4E (0.66) | HRH3KDM4ETP53CHRNA10CHRNA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |