Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132623 | 1.00 | MEN1 (0.49) | MEN1KMT2AHRH3POLB | |
| SCHEMBL6132213 | 0.85 | KMT2A (0.49) | MEN1KMT2AHRH3 | |
| SCHEMBL6134672 | 0.84 | MEN1 (0.49) | MEN1KMT2AHRH3 | |
| SCHEMBL6132625 | 0.84 | MEN1 (0.49) | MEN1KMT2AHRH3 | |
| SCHEMBL6135370 | 0.83 | USP2 (0.55) | MEN1KMT2AHRH3 | |
| SCHEMBL6135376 | 0.83 | USP2 (0.55) | MEN1KMT2AHRH3 | |
| SCHEMBL6134791 | 0.82 | MEN1 (0.49) | MEN1KMT2AHRH3 | |
| SCHEMBL6134795 | 0.82 | MEN1 (0.49) | MEN1KMT2AHRH3 | |
| SCHEMBL6132464 | 0.78 | ALDH1A1 (0.45) | MEN1KMT2AHRH3POLB | |
| SCHEMBL6134157 | 0.77 | HRH3 (0.44) | MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884774-B2 | Cyclic hexapeptide derivatives | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-04-26 | — | — | US | claimed |
| EP-1259535-B1 | CYCLIC HEXAPEPTIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-04-13 | — | — | EP | claimed |