Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ACACB | O00763 | 3/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6133198 | 1.00 | MAPT (0.50) | MAPTLMNAL3MBTL1ACACBHAO1 | |
| SCHEMBL6320559 | 0.88 | NR5A1 (0.56) | MAPTLMNAL3MBTL1GAANR5A1 | |
| SCHEMBL6719797 | 0.88 | MAPT (0.47) | MAPTLMNAL3MBTL1ACACBHAO1 | |
| SCHEMBL6324406 | 0.88 | NR5A1 (0.56) | MAPTLMNAL3MBTL1GAANR5A1 | |
| SCHEMBL7690566 | 0.84 | RARB (0.54) | MAPTLMNAL3MBTL1GAANR5A1 | |
| SCHEMBL6724461 | 0.82 | MAPT (0.50) | MAPTLMNAL3MBTL1ACACBHAO1 | |
| SCHEMBL23169795 | 0.81 | MAPT (0.50) | MAPTLMNAL3MBTL1ACACBHAO1 | |
| SCHEMBL27573986 | 0.79 | L3MBTL1 (0.50) | MAPTLMNAL3MBTL1ACACBHAO1 | |
| SCHEMBL29018693 | 0.78 | L3MBTL1 (0.66) | MAPTLMNAL3MBTL1ACACBHAO1 | |
| SCHEMBL17481962 | 0.77 | ACACB (0.45) | MAPTACACBHAO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |