Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.38 |
| ▸ | APP | P05067 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132815 | 0.87 | ALDH1A1 (0.41) | HRH3APPUSP2PTPN11HSD11B1 | |
| SCHEMBL13098814 | 0.86 | HRH3 (0.39) | HRH3APPUSP2PTPN11NPC1 | |
| SCHEMBL6132510 | 0.86 | PDE4D (0.44) | HRH3USP2PDE4DPDE7A | |
| SCHEMBL6134549 | 0.85 | KDM4E (0.43) | HRH3APPNPC1RAB9A | |
| SCHEMBL6132560 | 0.85 | PDE4D (0.48) | HRH3USP2NPC1RAB9APDE4D | |
| SCHEMBL6374773 | 0.84 | USP2 (0.43) | HRH3USP2PDE4DPDE7A | |
| SCHEMBL6376063 | 0.84 | PDE4D (0.46) | HRH3USP2NPC1RAB9APDE4D | |
| SCHEMBL6134823 | 0.82 | HRH3 (0.38) | HRH3USP2PDE4DPDE7A | |
| SCHEMBL13098866 | 0.81 | HRH3 (0.47) | HRH3PTPN11 | |
| SCHEMBL3110248 | 0.81 | HRH3 (0.34) | HRH3APPUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884774-B2 | Cyclic hexapeptide derivatives | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-04-26 | — | — | US | claimed |