Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 8/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 8/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 0.42 |
| ▸ | MGAM | O43451 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SI | P14410 | 3/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113153 | 0.85 | PIM1 (0.42) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL13098826 | 0.83 | PIM1 (0.43) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL7325194 | 0.82 | GAA (0.53) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL6134446 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL8160141 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL6134574 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL6134325 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL6135056 | 0.78 | RAB9A (0.57) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL6134549 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL13098863 | 0.77 | HRH3 (0.34) | ALDH1A1TP53MAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |