Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132850 | 0.89 | MAPT (0.38) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL6132775 | 0.86 | MAPT (0.42) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL6134575 | 0.85 | TP53 (0.43) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL6134854 | 0.85 | TP53 (0.45) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL6133896 | 0.84 | TP53 (0.42) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL6134951 | 0.81 | CA12 (0.52) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL6132169 | 0.81 | MAPT (0.43) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL6132626 | 0.81 | TP53 (0.46) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL6134517 | 0.78 | TP53 (0.50) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL6135097 | 0.77 | MAPT (0.45) | MAPTTP53CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |