Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132918 | 0.89 | MAPT (0.40) | MAPTGAACA12CA1CA2 | |
| SCHEMBL6132652 | 0.87 | MAPT (0.40) | MAPTGAATP53THRBLMNA | |
| SCHEMBL6134755 | 0.80 | MAPT (0.43) | MAPTGAACA12CA1CA2 | |
| SCHEMBL6132775 | 0.75 | MAPT (0.42) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL6132854 | 0.74 | MAPT (0.39) | MAPTGAACA12CA1CA2 | |
| SCHEMBL6134575 | 0.74 | TP53 (0.43) | MAPTGAACA12CA1CA2 | |
| SCHEMBL6134854 | 0.74 | TP53 (0.45) | MAPTGAACA12CA1CA2 | |
| SCHEMBL6132659 | 0.73 | MAPT (0.38) | MAPTGAACA12CA1CA2 | |
| SCHEMBL6134753 | 0.73 | MAPT (0.39) | MAPTGAACA12CA1CA2 | |
| SCHEMBL6133896 | 0.73 | TP53 (0.42) | MAPTGAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |