Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951762 | 0.93 | HPGD (0.55) | HPGDHTTALDH1A1TSHRMEN1 | |
| SCHEMBL20188098 | 0.87 | HPGD (0.65) | HPGDHTTALDH1A1TSHRMEN1 | |
| SCHEMBL22015905 | 0.87 | HPGD (0.65) | HPGDHTTALDH1A1TSHRMEN1 | |
| SCHEMBL20187714 | 0.86 | HPGD (0.59) | HPGDHTTALDH1A1TSHRMEN1 | |
| SCHEMBL4126209 | 0.85 | ALDH1A1 (0.55) | HPGDHTTALDH1A1MEN1KMT2A | |
| SCHEMBL2941901 | 0.85 | HTT (0.55) | HPGDHTTALDH1A1TSHRMEN1 | |
| SCHEMBL28242074 | 0.84 | HPGD (0.61) | HPGDHTTALDH1A1TSHRMEN1 | |
| SCHEMBL3898465 | 0.84 | HPGD (0.61) | HPGDHTTALDH1A1TSHRMEN1 | |
| SCHEMBL2947812 | 0.83 | ALDH1A1 (0.64) | HPGDHTTALDH1A1TSHRMEN1 | |
| SCHEMBL3900474 | 0.83 | SIRT2 (0.60) | HPGDHTTALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |