Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.47 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.47 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132350 | 0.96 | MEN1 (0.74) | MEN1KMT2AUSP2ITGB3ITGA2B | |
| SCHEMBL6132349 | 0.96 | MEN1 (0.74) | MEN1KMT2AUSP2ITGB3ITGA2B | |
| SCHEMBL1305974 | 0.90 | USP2 (0.63) | MEN1KMT2AUSP2ITGB3ITGA2B | |
| SCHEMBL4553154 | 0.84 | L3MBTL3 (0.57) | MEN1KMT2AUSP2ITGB3ITGA2B | |
| SCHEMBL1304508 | 0.84 | USP2 (0.59) | MEN1KMT2AUSP2ITGB3ITGA2B | |
| SCHEMBL6132707 | 0.82 | KMT2A (0.70) | MEN1KMT2AITGB3ITGA2BALOX15 | |
| SCHEMBL6132216 | 0.82 | MEN1 (0.70) | MEN1KMT2AITGB3ITGA2BALOX15 | |
| SCHEMBL6132703 | 0.82 | KMT2A (0.70) | MEN1KMT2AITGB3ITGA2BALOX15 | |
| SCHEMBL6134910 | 0.82 | USP2 (0.67) | MEN1KMT2AUSP2ITGB3ITGA2B | |
| SCHEMBL6135516 | 0.82 | USP2 (0.67) | MEN1KMT2AUSP2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |