Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | CASP6 | P55212 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23126615 | 0.83 | CASP6 (0.73) | USP2CYP2C19CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL6132593 | 0.79 | GFER (0.59) | USP2CYP2C19CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL3096735 | 0.79 | CYP2C9 (1.00) | USP2CYP2C19CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL18711490 | 0.78 | USP2 (0.55) | USP2CYP2C19CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL82046 | 0.78 | GFER (0.71) | CYP2C19CYP2C9ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL1128293 | 0.78 | GFER (0.71) | CYP2C19CYP2C9ALDH1A1MAPK1HPGD | |
| Hydrochloric Acid SCHEMBL6133093 | 0.77 | KDM4E (0.57) | USP2CYP2C19CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL2951680 | 0.77 | KDM4E (0.60) | USP2CYP2C19CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL10512362 | 0.77 | GFER (0.65) | USP2CYP2C19CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL10466780 | 0.77 | USP2 (0.53) | USP2CYP2C19CYP2C9ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |