Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132307 | 0.89 | ALDH1A1 (0.43) | MAPTPKMALDH1A1PTGER4TSHR | |
| SCHEMBL2936640 | 0.78 | CA12 (0.56) | MAPTPKMALDH1A1TSHRLTB4R | |
| SCHEMBL28823832 | 0.78 | SLC16A3 (0.46) | ALDH1A1PTGER4TP53TSHRPLA2G4B | |
| SCHEMBL6132715 | 0.77 | ALDH1A1 (0.44) | MAPTPKMALDH1A1TP53TSHR | |
| SCHEMBL27771418 | 0.75 | ALDH1A1 (0.43) | MAPTPKMALDH1A1PTGER4TP53 | |
| SCHEMBL15554479 | 0.74 | RARB (0.61) | MAPTALDH1A1TP53TSHRPLA2G4B | |
| SCHEMBL28182586 | 0.74 | ALDH1A1 (0.43) | MAPTALDH1A1PTGER4TP53TSHR | |
| SCHEMBL28427204 | 0.72 | ALDH1A1 (0.48) | MAPTALDH1A1PTGER4TP53TSHR | |
| SCHEMBL1127903 | 0.71 | MAPT (0.40) | MAPTALDH1A1TSHR | |
| SCHEMBL29673324 | 0.71 | MAPT (0.50) | MAPTCDC25BPKMALDH1A1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |