Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 10/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6133985 | 0.88 | ADORA1 (0.40) | ADORA1ADORA2AADORA2BRAB9ANPC1 | |
| SCHEMBL6134466 | 0.88 | ADORA1 (0.53) | ADORA1SRCADORA2AADORA2BMAPT | |
| SCHEMBL6134132 | 0.88 | ADORA1 (0.41) | ADORA1ADORA2AADORA2BALDH1A1DHFR | |
| SCHEMBL6134599 | 0.88 | ADORA1 (0.53) | ADORA1SRCADORA2AADORA2BDHFR | |
| SCHEMBL6134324 | 0.88 | ADORA1 (0.47) | ADORA1ADORA2AADORA2B | |
| SCHEMBL6134159 | 0.87 | RPS6KA3 (0.46) | ADORA1ADORA2AADORA2BRPS6KA3 | |
| SCHEMBL6134637 | 0.87 | ADORA2A (0.56) | ADORA1SRCADORA2AADORA2BRAB9A | |
| SCHEMBL6134331 | 0.86 | ADORA1 (0.45) | ADORA1SRCADORA2AADORA2BDHFR | |
| SCHEMBL6134489 | 0.86 | ADORA1 (0.55) | ADORA1SRCADORA2AXDHALDH1A1 | |
| SCHEMBL6133534 | 0.86 | ADORA1 (0.57) | ADORA1ADORA2AADORA2BXDHRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043315-A1 | Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them | ASTELLAS PHARMA INC. (JP) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043315-A1 | Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them | ADORA2B, ADORA2A, ADORA1 | ADORA1 3/4885SRC 2622/4885ADORA2A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.