Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901028 | 0.89 | KDM4E (0.59) | HRH3KCNH2ALDH1A1TSHRTHRA | |
| Hydrochloric Acid SCHEMBL10897562 | 0.88 | KDM4E (0.58) | HRH3KCNH2ALDH1A1TSHRTHRA | |
| SCHEMBL6132957 | 0.87 | HRH3 (0.55) | HRH3KCNH2ALDH1A1TSHRCACNA1F | |
| SCHEMBL6133614 | 0.86 | DRD3 (0.52) | HRH3KCNH2ALDH1A1TSHRMEN1 | |
| SCHEMBL3196580 | 0.85 | HSD17B10 (0.53) | HRH3KCNH2ALDH1A1TSHRMEN1 | |
| SCHEMBL6135617 | 0.85 | MAPT (0.51) | HRH3ALDH1A1TSHRHTTDRD3 | |
| SCHEMBL8205972 | 0.83 | ALDH1A1 (0.58) | KCNH2ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6134554 | 0.83 | HRH3 (0.51) | HRH3MEN1KMT2ADRD3 | |
| SCHEMBL3196574 | 0.83 | ALDH1A1 (0.53) | HRH3KCNH2ALDH1A1TSHRMEN1 | |
| SCHEMBL6132804 | 0.83 | HPGD (0.46) | HRH3KCNH2ALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261177-A1 | Compound | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | US | disclosed |
| EP-1366066-A2 | CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002072621-A2 | CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261177-A1 | Compound | MANBA, MAN2B1, MAN2A1 | HRH3 1440/4885KCNH2 2774/4885ALDH1A1 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.