SCHEMBL6134821

SCHEMBL6134821

c1ccc(N(c2ccccc2)C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.52
ALDH1A1 P00352 6/20 0.39
TSHR P16473 2/20 0.39
ALOX15 P16050 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323982 0.82 CA4 (0.46) KCNN4KDM4EKMT2A
SCHEMBL29323970 0.82 CA4 (0.46) KCNN4KDM4EKMT2A
SCHEMBL9748496 0.76 KCNN4 (0.33) KCNN4ALDH1A1CYP1A2CYP3A4KDM4E
SCHEMBL30385177 0.74 ALDH1A1 (0.39) KCNN4ALDH1A1ALOX15NPSR1MAPK1
SCHEMBL23749591 0.74 KCNN4 (0.55) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL2038162 0.74 KCNN4 (0.42) KCNN4ALDH1A1TSHRALOX15MAPK1
SCHEMBL11428040 0.74 KCNN4 (0.48) KCNN4ALDH1A1TSHRALOX15NPSR1
SCHEMBL8374359 0.74 KCNN4 (0.48) KCNN4ALDH1A1TSHRALOX15NPSR1
SCHEMBL14857236 0.73 KCNN4 (0.60) KCNN4ALDH1A1TSHRALOX15MAPK1
SCHEMBL10425497 0.72 KCNN4 (0.58) KCNN4ALDH1A1TSHRMAPK1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239974-A1 RESIN COMPOSITION, PREPREG USING SAME, FILM PROVIDED WITH RESIN, METAL FOIL PROVIDED WITH RESIN, METAL-CLAD LAMINATE, AND WIRING BOARD PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2024-07-18 US disclosed
US-20240239974-A1 RESIN COMPOSITION, PREPREG USING SAME, FILM PROVIDED WITH RESIN, METAL FOIL PROVIDED WITH RESIN, METAL-CLAD LAMINATE, AND WIRING BOARD PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2024-07-18 US disclosed
CN-102834463-B Use of polyamides resistant to corrosion and stress cracking BASF SE 2015-01-28 CN disclosed
CN-101977996-B Polyamide nanocomposites with hyper-branched polyetheramines BASF SE 2013-01-02 CN disclosed
CN-102834463-A Use of polyamides resistant to corrosion and stress cracking BASF SE 2012-12-19 CN disclosed
CN-101977996-A Polyamide nanocomposites with hyper-branched polyetheramines BASF SE 2011-02-16 CN disclosed
CN-101573413-A Thermoplastic molding compositions with improved ductility BASF SE (DE) 2009-11-04 CN disclosed
US-20050067951-A1 For example, N,N'-bis-(4'-(N-triphenylmethyl)-phenyl)-N-naphth-1-yl-amino)-bi-phenylyl)-N,N'-bisphenyl-2,7-amino-9-phenylcarbazole; hole transfer material SENSIENT IMAGING TECHNOLOGIES GMBH 2005-03-31 US disclosed
EP-1470100-A1 TRIARYLAMINE DERIVATIVES AND THE USE THEREOF IN ORGANIC ELECTROLUMINESCENT AND ELECTROPHOTOGRAPHIC DEVICES Sensient Imaging Technologies GmbH (DE) 2004-10-27 EP disclosed
WO-2003064373-A1 TRIARYLAMINE DERIVATIVES AND THE USE THEREOF IN ORGANIC ELECTROLUMINESCENT AND ELECTROPHOTOGRAPHIC DEVICES SENSIENT IMAGING TECHNOLOGIES GMBH (DE) 2003-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050067951-A1 For example, N,N'-bis-(4'-(N-triphenylmethyl)-phenyl)-N-naphth-1-yl-amino)-bi-phenylyl)-N,N'-bisphenyl-2,7-amino-9-phenylcarbazole; hole transfer material NAT1, NUCB2, PNN KCNN4 176/4885ALDH1A1 2424/4885TSHR 1351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.