Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027900 | 0.80 | GAA (0.38) | GAAHTTADORA1ADORA3ADORA2A | |
| SCHEMBL3401142 | 0.78 | TP53 (0.41) | GAAHTTADORA1ADORA3ADORA2A | |
| SCHEMBL6134710 | 0.72 | — | — | |
| SCHEMBL10859287 | 0.72 | — | — | |
| SCHEMBL6134846 | 0.68 | GAA (0.38) | GAAHTTADORA1ADORA3ADORA2A | |
| SCHEMBL895 | 0.65 | GLA (0.37) | HTT | |
| SCHEMBL9418179 | 0.65 | NPSR1 (0.30) | — | |
| SCHEMBL3405385 | 0.65 | ALK (0.42) | GAAHTTADORA1ADORA3ADORA2A | |
| SCHEMBL3027998 | 0.65 | GAA (0.39) | GAAHTTADORA1ADORA3ADORA2A | |
| SCHEMBL27349364 | 0.65 | ADORA3 (0.42) | GAAHTTADORA1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082414-A2 | CONCOMITANT DRUGS OF A SULFONAMIDE AND ANOTHER THERAPEUTIC AGENT | ASTELLAS PHARMA INC. (JP) | 2005-09-09 | — | — | WO | disclosed |
| US-20050197376-A1 | Concomitant drugs | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-09-08 | — | — | US | disclosed |