Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 2/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6132415 | 0.82 | SLC18A3 (0.44) | CSNK2A2CSNK2BCSNK2A1HRH3SLC18A3 | |
| Trifluoroacetic Acid SCHEMBL27007668 | 0.70 | ALDH1A1 (0.36) | HRH3GAAALDH1A1SMN1; SMN2HRH4 | |
| Hydrochloric Acid SCHEMBL6135236 | 0.68 | MKNK1 (0.47) | SLC18A3ESRRGESRRBESR1 | |
| Hydrochloric Acid SCHEMBL6135233 | 0.67 | TP53 (0.44) | SLC18A3ESRRGESRRBESR1 | |
| SCHEMBL6134375 | 0.67 | HRH3 (0.52) | HRH3ALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL7317798 | 0.65 | CSNK2A2 (0.59) | CSNK2A2CSNK2BCSNK2A1GPR119MGAM | |
| SCHEMBL6135618 | 0.64 | HRH3 (0.50) | HRH3SLC18A3ESRRGESRRBESR1 | |
| Trifluoroacetic Acid SCHEMBL6133865 | 0.63 | MAOB (0.40) | CSNK2A2CSNK2BCSNK2A1HRH3SLC18A3 | |
| SCHEMBL6134406 | 0.62 | HRH3 (0.53) | CSNK2A2CSNK2BCSNK2A1HRH3ESRRG | |
| SCHEMBL6134222 | 0.62 | HRH3 (0.53) | CSNK2A2CSNK2BCSNK2A1HRH3ESRRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261177-A1 | Compound | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261177-A1 | Compound | MANBA, MAN2B1, MAN2A1 | CSNK2A2 1527/4885CSNK2B 900/4885CSNK2A1 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.