Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | MGLL | Q99685 | 4/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6373698 | 0.85 | HDAC3 (0.49) | NPC1RAB9AALDH1A1HDAC6HDAC3 | |
| SCHEMBL7324635 | 0.85 | HDAC3 (0.53) | NPC1RAB9AALDH1A1HDAC6HDAC3 | |
| SCHEMBL6236412 | 0.84 | HDAC3 (0.45) | NPC1RAB9AALDH1A1HDAC6HDAC3 | |
| SCHEMBL6374827 | 0.83 | HDAC3 (0.48) | NPC1RAB9AALDH1A1HDAC6HDAC3 | |
| SCHEMBL6132174 | 0.83 | HDAC3 (0.44) | NPC1RAB9AALDH1A1HDAC6HDAC3 | |
| SCHEMBL6133706 | 0.82 | HDAC3 (0.47) | NPC1RAB9AALDH1A1HDAC6HDAC3 | |
| SCHEMBL6134003 | 0.81 | HDAC3 (0.47) | NPC1RAB9AHDAC6HDAC3HDAC4 | |
| SCHEMBL6134745 | 0.81 | CHKA (0.50) | ALDH1A1HDAC6HDAC1HTTPOLB | |
| SCHEMBL6134110 | 0.80 | HDAC3 (0.46) | NPC1RAB9AHDAC6HDAC3HDAC4 | |
| SCHEMBL6238210 | 0.80 | HDAC3 (0.48) | NPC1RAB9AALDH1A1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261177-A1 | Compound | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261177-A1 | Compound | MANBA, MAN2B1, MAN2A1 | NPC1 1070/4885RAB9A 3326/4885ALDH1A1 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.