Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610723 | 0.89 | SMN1; SMN2 (0.51) | HTTSMN1; SMN2LMNAKCNA5L3MBTL1 | |
| SCHEMBL21985416 | 0.87 | SMN1; SMN2 (0.55) | HTTSMN1; SMN2LMNAKCNA5TGM2 | |
| SCHEMBL292084 | 0.87 | SMN1; SMN2 (0.55) | HTTSMN1; SMN2LMNAKCNA5TGM2 | |
| SCHEMBL25281617 | 0.86 | HTT (0.59) | HTTSMN1; SMN2LMNAKCNA5L3MBTL1 | |
| SCHEMBL1610973 | 0.85 | SMN1; SMN2 (0.48) | HTTSMN1; SMN2LMNAKCNA5TGM2 | |
| SCHEMBL13741500 | 0.84 | SMN1; SMN2 (0.59) | HTTSMN1; SMN2LMNATGM2L3MBTL1 | |
| SCHEMBL19527405 | 0.84 | SMN1; SMN2 (0.52) | HTTSMN1; SMN2LMNAKCNA5L3MBTL1 | |
| SCHEMBL25448079 | 0.83 | PPID (0.46) | HTTSMN1; SMN2LMNAKCNA5L3MBTL1 | |
| SCHEMBL18002248 | 0.83 | SMN1; SMN2 (0.58) | HTTSMN1; SMN2LMNATGM2L3MBTL1 | |
| SCHEMBL19527210 | 0.83 | SMN1; SMN2 (0.51) | HTTSMN1; SMN2LMNAKCNA5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908911-B1 | Antibacterial agents | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2005-06-21 | — | — | US | disclosed |
| EP-1210330-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-04-20 | — | — | EP | disclosed |
| EP-1210330-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001010835-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-02-15 | — | — | WO | disclosed |