SCHEMBL6135864

SCHEMBL6135864

O=C1C=CC(=O)N1c1ccccc1CC(F)(F)F

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.65
TLR9 Q9NR96 2/20 0.55
FAAH O00519 3/20 0.47
ALDH1A1 P00352 1/20 0.40
HSP90AA1 P07900 1/20 0.40
PKM P14618 1/20 0.40
CCR6 P51684 1/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 1/20 0.38
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
LMNA P02545 2/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18812467 0.82 MGLL (0.70) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL9711353 0.79 MGLL (0.71) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL8352899 0.79 MGLL (0.77) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL8439293 0.79 MGLL (0.77) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL29510771 0.79 MGLL (1.00) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL1535499 0.79 MGLL (1.00) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL28743242 0.78 MGLL (0.59) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL31166666 0.76 MGLL (0.71) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL10400690 0.76 MGLL (0.71) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL28752499 0.76 MGLL (0.71) MGLLTLR9FAAHALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0984931-B1 AROMATIC MALEIMIDES AND THEIR USE AS PHOTOINITIATORS ALBEMARLE CORP (US) 2005-02-09 EP claimed
EP-0984931-A1 AROMATIC MALEIMIDES AND THEIR USE AS PHOTOINITIATORS First Chemical Corporation (US) 2000-03-15 EP claimed
WO-1998054134-A1 AROMATIC MALEIMIDES AND THEIR USE AS PHOTOINITIATORS FIRST CHEMICAL COPORATION (US) 1998-12-03 WO claimed