Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136569 | 0.92 | ALDH1A1 (0.52) | KMT2AALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL10648648 | 0.86 | KMT2A (0.48) | KMT2AALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL27339301 | 0.83 | ALDH1A1 (0.49) | KMT2AALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL4989111 | 0.81 | KMT2A (0.50) | KMT2AALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL16839883 | 0.81 | SMN1; SMN2 (0.56) | KMT2AALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL11284225 | 0.80 | ALDH1A1 (0.46) | KMT2AALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL12717220 | 0.80 | ALDH1A1 (0.46) | KMT2AALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL4396522 | 0.79 | KMT2A (0.59) | KMT2ATSHRMEN1 | |
| SCHEMBL22762568 | 0.78 | KMT2A (0.55) | KMT2ATSHRSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13045302 | 0.77 | KMT2A (0.52) | KMT2AALDH1A1MAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042279-B1 | SUBSTITUTED BETA-ALANINES | AVENTIS PHARMA LTD (GB) | 2005-03-02 | — | — | EP | disclosed |
| US-6352977-B1 | ALANINE WITH PRODRUGS | AVENTIS PHARMA LIMITED (GB) | 2002-03-05 | — | — | US | disclosed |
| EP-1042279-A1 | SUBSTITUTED BETA-ALANINES | Aventis Pharma Limited (GB) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033789-A1 | SUBSTITUTED β-ALANINES | AVENTIS PHARMA LIMITED (GB) | 1999-07-08 | — | — | WO | disclosed |