Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.38 |
| ▸ | IARS1 | P41252 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL542821 | 0.90 | DPP4 (0.41) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL3930248 | 0.89 | DPP4 (0.46) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL5161688 | 0.89 | DPP4 (0.46) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL1537300 | 0.88 | DPP4 (0.40) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL1537380 | 0.88 | DPP4 (0.40) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL13324435 | 0.86 | ALDH1A1 (0.50) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL598472 | 0.86 | ALDH1A1 (0.50) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL19927408 | 0.83 | DPP4 (0.37) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL27453775 | 0.83 | DPP4 (0.37) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL1537392 | 0.83 | DPP4 (0.42) | DPP4DPP8DPP9DPP7IARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946499-B1 | N-(ARYL/HETEROARYL/ALKYLACETYL) AMINO ACID AMIDES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | ELAN PHARM INC (US) | 2005-06-01 | — | — | EP | claimed |
| EP-0946499-B1 | N-(ARYL/HETEROARYL/ALKYLACETYL) AMINO ACID AMIDES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | ELAN PHARM INC (US) | 2005-06-01 | — | — | EP | disclosed |