Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | NPY2R | P49146 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985439 | 0.95 | NPY2R (0.46) | SLC9A1CYP3A4CYP2C19NPY2RMEN1 | |
| Hydrochloric Acid SCHEMBL6137232 | 0.91 | NPY2R (0.55) | SLC9A1CYP3A4CYP2C19NPY2RMEN1 | |
| Hydrochloric Acid SCHEMBL7988911 | 0.87 | SLC9A1 (0.48) | SLC9A1CYP3A4CYP2C19NPY2RMEN1 | |
| Hydrochloric Acid SCHEMBL6137329 | 0.85 | NPY2R (0.51) | SLC9A1CYP3A4CYP2C19NPY2RMEN1 | |
| Sabiporide SCHEMBL29385812 | 0.84 | SLC9A1 (0.70) | SLC9A1CYP3A4CYP2C19NPY2R | |
| Sabiporide SCHEMBL1286662 | 0.84 | SLC9A1 (0.70) | SLC9A1CYP3A4CYP2C19NPY2R | |
| SCHEMBL7612077 | 0.83 | MAPT (0.52) | SLC9A1CYP3A4CYP2C19MEN1KMT2A | |
| Sabiporide SCHEMBL1286645 | 0.83 | SLC9A1 (0.69) | SLC9A1CYP3A4CYP2C19NPY2R | |
| Sabiporide SCHEMBL4901732 | 0.82 | SLC9A1 (0.68) | SLC9A1CYP3A4CYP2C19NPY2R | |
| SCHEMBL1763080 | 0.82 | SLC9A1 (0.68) | SLC9A1CYP3A4CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165534-B1 | BENZOYLGUANIDINE DERIVATIVES WITH ADVANTAGEOUS PROPERTIES, METHOD FOR PRODUCING THEM AND THEIR USE IN THE PRODUCTION OF MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-02-02 | — | — | EP | claimed |
| EP-1165534-A2 | BENZOYLGUANIDINE DERIVATIVES WITH ADVANTAGEOUS PROPERTIES, METHOD FOR PRODUCING THEM AND THEIR USE IN THE PRODUCTION OF MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000017176-A2 | BENZOYLGUANIDINE DERIVATIVES WITH ADVANTAGEOUS PROPERTIES, METHOD FOR PRODUCING THEM AND THEIR USE IN THE PRODUCTION OF MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-03-30 | — | — | WO | disclosed |