SCHEMBL613747

SCHEMBL613747

Clc1cc2cc[nH]c2cc1Cl

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.69
AHR P35869 7/20 0.58
NR4A2 P43354 2/20 0.58
CMA1 P23946 1/20 0.58
F7 P08709 1/20 0.58
LTA4H P09960 1/20 0.58
F3 P13726 1/20 0.58
GPR84 Q9NQS5 1/20 0.54
CYP2A6 P11509 3/20 0.46
TYR P14679 1/20 0.46
USP2 O75604 1/20 0.46
GAA P10253 1/20 0.46
ALOX15 P16050 1/20 0.46
RAD51 Q06609 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
TRPA1 O75762 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL9446755 0.86 CSNK2A1 (0.55) CSNK2A1AHRNR4A2CMA1F7
SCHEMBL30593539 0.82 GPR84 (0.69) CSNK2A1AHRNR4A2CMA1F7
SCHEMBL1076943 0.82 CSNK2A1 (0.85) CSNK2A1AHRNR4A2CMA1F7
SCHEMBL10179972 0.82 CSNK2A1 (1.00) CSNK2A1AHRNR4A2CMA1F7
SCHEMBL5496842 0.82 CSNK2A1 (0.55) CSNK2A1AHRNR4A2CMA1F7
SCHEMBL2936352 0.82 CSNK2A1 (0.60) CSNK2A1AHRNR4A2CMA1F7
SCHEMBL15372398 0.82 CSNK2A1 (0.55) CSNK2A1AHRNR4A2CMA1F7
SCHEMBL615624 0.82 CSNK2A1 (0.60) CSNK2A1AHRNR4A2CMA1F7
SCHEMBL397084 0.82 CSNK2A1 (0.55) CSNK2A1AHRNR4A2CMA1F7
SCHEMBL1196529 0.82 GPR84 (0.69) CSNK2A1AHRNR4A2CMA1F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805664-B Bionic modified marine antifouling resin material, and preparation method and application thereof 江苏苏博特新材料股份有限公司 2023-04-14 CN claimed
CN-112574093-B Novel green method for preparing 3-diaryl methyl substituted indole compound 湖南理工学院 2022-10-04 CN claimed
CN-114805664-A Bionic modified marine antifouling resin material, and preparation method and application thereof 江苏苏博特新材料股份有限公司 2022-07-29 CN claimed
CN-114292582-B Hyperbranched coating suitable for marine concrete, and preparation method and application thereof 江苏苏博特新材料股份有限公司 2022-07-12 CN claimed
CN-114292582-A Hyperbranched coating suitable for marine concrete, and preparation method and application thereof 江苏苏博特新材料股份有限公司 2022-04-08 CN claimed
CN-112574093-A Novel green method for preparing 3-diaryl methyl substituted indole compound 湖南理工学院 2021-03-30 CN claimed
CN-103664736-B A kind of ester derivative containing acrylamido indoles and its preparation method and application OCEAN UNIVERSITY OF CHINA (CN) 2015-09-30 CN claimed
CN-103694160-B Amide derivative containing double-bond gramine and preparation method and application thereof OCEAN UNIV CHINA 2015-04-15 CN claimed
CN-103694160-A Amide derivative containing double-bond gramine and preparation method and application thereof OCEAN UNIV CHINA 2014-04-02 CN claimed
CN-103664736-A Ester derivative containing acrylamide indole, preparation method and application thereof OCEAN UNIV CHINA 2014-03-26 CN claimed
CN-1233630-C N-substituted indole derivative preparation method OCEAN UNIV CHINA (CN) 2005-12-28 CN claimed
CN-1544419-A N-substituted indole derivative preparation method 中国海洋大学 2004-11-10 CN claimed
JP-8034770-A None JP disclosed
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US disclosed
US-12522572-B2 Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-01-13 US disclosed
US-12479807-B2 Methods using HDAC11 inhibitors VALO HEALTH, INC. (US) 2025-11-25 US disclosed
EP-0707581-A1 INDOLINE DERIVATIVES AS 5HT 2C? ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1996-04-24 EP disclosed
JP-H0834770-A ANTIFOULING AGENT AGAINST UNDERWATER ADHERENT ORGANISM IHARA CHEM IND CO LTD 1996-02-06 JP disclosed
WO-1995023141-A1 4-HETEROCYCLYL-SUBSTITUTED QUINAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS ANTI-CANCER AGENTS PFIZER INC. (US) 1995-08-31 WO disclosed
WO-1995001976-A1 INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1995-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS HDAC3, HDAC1, HDAC4 CSNK2A1 351/4885AHR 406/4885NR4A2 122/4885
US-12479807-B2 Methods using HDAC11 inhibitors HDAC11, HDAC1, HDAC10 CSNK2A1 476/4885AHR 3599/4885NR4A2 1961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.