SCHEMBL613748

SCHEMBL613748

O=Cc1cc(Cl)ccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29940193 1.00
SCHEMBL28330238 0.89 FGFR4 (0.39)
SCHEMBL20746197 0.84
SCHEMBL28778071 0.79 MAP4K4 (0.49)
SCHEMBL15741441 0.79
SCHEMBL27751607 0.78 MAP4K4 (0.46)
SCHEMBL5017727 0.77
SCHEMBL1987438 0.77
SCHEMBL29114894 0.77
SCHEMBL15741547 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 551 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112920175-B Coumarin-based palladium ion fluorescent probe compound and preparation method thereof 吉林大学 2022-05-31 CN claimed
CN-112920175-A Coumarin-based palladium ion fluorescent probe compound and preparation method thereof 吉林大学 2021-06-08 CN claimed
CN-110467566-A Aryl phenyl-diformyl hydrazine class compound and preparation method thereof UNIV NANJING SCI & TECH 2019-11-19 CN claimed
CN-105859612-A Sorafenib preparation method 山东康美乐医药科技有限公司 2016-08-17 CN claimed
EP-1065206-B1 Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents PFIZER (US) 2002-10-09 EP claimed
CN-121226265-B Acylhydrazone compound containing quinazolinone fragment, and preparation method and application thereof BOZHOU UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-116854630-B Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections 吉利德科学公司 2026-05-19 CN disclosed
US-20260092045-A1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2026-04-02 US disclosed
US-12582645-B2 Chemokine CXCR4 receptor modulators and uses related thereto EMORY UNIVERSITY (US) 2026-03-24 US disclosed
US-12558341-B2 Oral complement factor D inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
EP-4262788-B1 UREA OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME LLC (US) 2026-01-21 EP disclosed
US-12522595-B2 Bicyclic ether O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranosidase inhibitors BIOGEN MA INC. (US) 2026-01-13 US disclosed
US-5541213-A ADENOSINE A1 RECEPTOR ANTAGONISTS, TREATMENT OF KIDNEY DISORDERS EISAI CO., LTD. (JP) 1996-07-30 US disclosed
CN-1111622-A Propenoic acid derivaties EISAI CO LTD (JP) 1995-11-15 CN disclosed
EP-0630894-A1 Propenoic acid derivatives as adenosine A1 antagonists Eisai Co., Ltd. (JP) 1994-12-28 EP disclosed
EP-0254856-B1 PYRIDINETHANOL AMINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1991-09-04 EP disclosed
US-4988714-A Drugs for treatment of obesity and diabetics, increases protein breakdown, for fattening animals HOFFMANN-LA ROCHE INC. (US) 1991-01-29 US disclosed
US-4800206-A ANTIDIABETIC AGENTS; HYPOGLYCEMIC AGENTS HOFFMANN-LA ROCHE INC. (US) 1989-01-24 US disclosed
EP-0254856-A2 Pyridinethanol amine derivatives F. HOFFMANN-LA ROCHE AG (CH) 1988-02-03 EP disclosed
EP-0129791-A2 Tetrahydropyridazinone derivatives, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1985-01-02 EP disclosed