Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609085 | 0.86 | ERN1 (0.38) | ERN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7609087 | 0.82 | ERN1 (0.50) | MAP4K4ERN1MAPT | |
| SCHEMBL28778071 | 0.82 | MAP4K4 (0.49) | MAP4K4ALOX5NFE2L2KMO | |
| SCHEMBL27863825 | 0.81 | ERN1 (0.39) | ERN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30479916 | 0.81 | FDPS (0.44) | ERN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25244672 | 0.81 | FDPS (0.44) | ERN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2084619 | 0.81 | EGFR (0.45) | MAP4K4CNR1ERN1ALDH1A1KMT2A | |
| SCHEMBL29935212 | 0.81 | EGFR (0.45) | MAP4K4CNR1ERN1ALDH1A1KMT2A | |
| SCHEMBL613748 | 0.78 | — | — | |
| SCHEMBL29940193 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101506149-A | Prolyl hydroxylase inhibitors and methods of use | PROCTER & GAMBLE (US) | 2009-08-12 | — | — | CN | claimed |
| CN-111051503-A | Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohol | 江南大学 | 2020-04-21 | — | — | CN | disclosed |
| CN-101506149-B | Prolyl hydroxylase inhibitors and methods of use | PROCTER & GAMBLE | 2012-11-14 | — | — | CN | disclosed |
| CN-101506149-A | Prolyl hydroxylase inhibitors and methods of use | PROCTER & GAMBLE (US) | 2009-08-12 | — | — | CN | disclosed |