Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 4/20 | 0.58 |
| ▸ | AMPD3 | Q01432 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3287578 | 0.88 | ADA (0.55) | ADAAMPD3ALDH1A1TP53HTT | |
| SCHEMBL8018528 | 0.86 | ADA (0.56) | ADAAMPD3ALDH1A1TP53HTT | |
| SCHEMBL41684 | 0.86 | ADA (0.61) | ADAAMPD3ALDH1A1TP53HTT | |
| SCHEMBL5555999 | 0.85 | ADA (0.63) | ADAAMPD3ALDH1A1TP53HTT | |
| SCHEMBL3819355 | 0.84 | ADA (0.53) | ADATP53TDP1 | |
| SCHEMBL5983456 | 0.84 | ADA (0.53) | ADATP53TDP1 | |
| SCHEMBL8018401 | 0.83 | ATIC (0.52) | SMN1; SMN2 | |
| SCHEMBL15348425 | 0.82 | ADA (0.60) | ADAAMPD3ALDH1A1TP53HTT | |
| SCHEMBL5503468 | 0.80 | ADA (0.48) | ADAAMPD3ALDH1A1TP53HTT | |
| SCHEMBL8840658 | 0.80 | ADA (0.60) | ADAAMPD3ALDH1A1TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1116032-A4 | GPR10 AS A TARGET FOR IDENTIFYING WEIGHT MODULATING COMPOUNDS | MILLENNIUM PHARM INC (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-1116032-A1 | GPR10 AS A TARGET FOR IDENTIFYING WEIGHT MODULATING COMPOUNDS | Millennium Pharmaceuticals, Inc. (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017641-A1 | GPR10 AS A TARGET FOR IDENTIFYING WEIGHT MODULATING COMPOUNDS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2000-03-30 | — | — | WO | disclosed |