Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663072 | 0.81 | TSHR (0.52) | TSHRLMNATAAR1ACHEBCHE | |
| SCHEMBL6053680 | 0.81 | TSHR (0.52) | TSHRLMNATAAR1ACHEBCHE | |
| SCHEMBL22091837 | 0.77 | TSHR (0.64) | TSHRLMNATAAR1ACHEBCHE | |
| SCHEMBL19190103 | 0.74 | LMNA (0.46) | TSHRLMNATAAR1ACHEBCHE | |
| SCHEMBL17019782 | 0.74 | TSHR (0.58) | TSHRLMNATAAR1ACHEBCHE | |
| SCHEMBL22110584 | 0.74 | TSHR (0.58) | TSHRLMNATAAR1ACHEBCHE | |
| SCHEMBL1928095 | 0.74 | TSHR (0.58) | TSHRLMNATAAR1ACHEBCHE | |
| SCHEMBL30210778 | 0.73 | TSHR (0.52) | TSHRLMNATAAR1ACHEBCHE | |
| SCHEMBL6138331 | 0.73 | TSHR (0.52) | TSHRLMNATAAR1ACHEBCHE | |
| SCHEMBL3814418 | 0.73 | TSHR (0.52) | TSHRLMNATAAR1ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170281-B1 | 1,1- and 1,2-disubstituted cyclopropanes, process for their preparation and pharmaceutical compositions thereof | SERVIER LAB (FR) | 2005-12-21 | — | — | EP | disclosed |
| EP-1170281-A1 | 1,1- and 1,2-disubstituted cyclopropanes, process for their preparation and pharmaceutical compositions thereof | LES LABORATOIRES SERVIER (FR) | 2002-01-09 | — | — | EP | disclosed |